Evaluation of iridociliary and lenticular elasticity using shear-wave elastography in rabbit eyes.
نویسندگان
چکیده
INTRODUCTION A previous study has employed shear-wave ultrasound elastographic imaging to assess corneal rigidity in an ex-vivo porcine eye model. This study employs the same modality in vivo in a rabbit eye model in order to assess lens, ciliary body and total ocular rigidity changes following the instillation of atropine and pilocarpine. METHODS Ten non-pigmented female rabbits were examined. Measurements of the lens, ciliary body and total ocular rigidity as well as lens thickness and anterior chamber depth were taken with the Aixplorer system (SuperSonic Imagine, Aix-en-Provence, France) with the SuperLinear™ SL 15-4 transducer in both eyes at baseline as well as after pilocarpine and atropine instillation. The IOP was also measured with the TonoPen tonometer. RESULTS Changes in rigidity in the examined areas following atropine instillation were statistically not significant. Ciliary body rigidity was significantly increased whereas lens and total ocular rigidity were significantly reduced following pilocarpine instillation. The decrease in lens rigidity following pilocarpine was significantly associated with the respective increase in ciliary body rigidity. CONCLUSIONS Shear-wave ultrasound elastography can detect in vivo rigidity changes in the anterior segment of the rabbit eye model and may potentially be applied in human eyes, providing useful clinical information on conditions in which rigidity changes play an important role, such as glaucoma, pseudoexfoliation syndrome or presbyopia.
منابع مشابه
Evaluation of the diagnostic function of shear wave elastography in the differentiation of malignant and benign breast masses and its relationship with histological factors
Background: Shear wave elastography (SWE) estimates the stiffness of a mass based on the velocity of shear wave propagation by sound waves. Due to higher cell density and angiogenesis, malignant masses have higher stiffness than benign ones. Methods: The present study was a prospective study and was performed on patients who were referred to Ahvaz Golestan Hospital with breast mass during Marc...
متن کاملQuantifying the passive stretching response of human tibialis anterior muscle using shear wave elastography.
BACKGROUND Quantifying passive stretching responses of individual muscles helps the diagnosis of muscle disorders and aids the evaluation of surgical/rehabilitation treatments. Utilizing an animal model, we demonstrated that shear elastic modulus measured by supersonic shear wave elastography increases linearly with passive muscle force. This study aimed to use this state-of-the-art technology ...
متن کاملQuantitative Evaluation of Elasticity in the Posteroinferior Shoulder Joint Capsules of Collegiate Baseball Players Using Shear-Wave Ultrasound Elastography
متن کامل
Elucidation of Isotropic and Anisotropic Shear Elasticity of in vivo Soft Tissue using Planar Magnetic Resonance
Magnetic resonance elastography (MRE) is a noninvasive method that allows the determination of in vivo shear elasticity of soft tissues. In this thesis methods for the determination of isotropic and anisotropic shear elasticities from MRE wave data were developed and evaluated. All methods presented in this work are based on planar MRE, i.e. they are based on the measurement of a single displac...
متن کاملThree dimensional shear wave scattering MR elastography
Introduction: Magnetic resonance elastography (MRE) is a non invasive method that combines externally applied vibrations with the motion sensitivity of MRI to measure the shear elasticity soft tissues [1]. In MRE this is traditionally achieved by solving an inverse problem with MRE shear wave images as input data [2]. A complementary approach, which does not require the solution of an inverse p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Acta medica
دوره 57 1 شماره
صفحات -
تاریخ انتشار 2014